Potassium Carbonate → HCID 21968288, compound

Participants

Reaction Conditions

Reaction Steps

A cooled (-10° C.) mixture containing L-phenylalanylchloromethylketone (3.2 mmole) in CH2Cl2 (30 ml) and potassium carbonate (10 mmole) in water (10 Ml) was treated with cyclohexanecarbonylchloride (3.2 mmole). The resulting mixture was stirred for two hours at ambient temperature. The organic layer was separated, washed with water (3×20 ml) and dried over anhydrous magnesium sulfate. Filtration and concentration in vacuo gave the titled compound as a cream colored solid (2.6 mmole, 8%).

Provenance & Evidence