Pyridine → HCID 18789372, compound

HRID 1106677Notes

Reaction equation

HRID 1106677 reaction equation
[OH:1][CH2:2][CH2:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][NH:5]1.[C:10](Cl)(=O)[O:11]C1C=CC=CC=1.[N:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.CN[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40]CCCCC.[CH2:46](Cl)Cl>>[OH:1][CH2:2][CH2:3][CH:4]1[CH2:9][CH2:8][CH2:7][CH2:6][N:5]1[C:10]([N:20]([CH3:46])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH3:40])=[O:11]

Participants

6

Reactant 5

HCID 1049PyridineHCID 6344DichloromethaneHCID 151442-Piperidin-2-ylethanolHCID 15891Phenyl chloroformateHCID 75539N-Methyloctadecylamine

Product 1

HCID 18789372HCID 18789372, compound

Procedure

[2-(2-Hydroxyethyl)piperidine is reacted with phenyl chlorocarbonate in methylene chloride in the presence of pyridine and further reacted with N-methyl-N-octadecylamine to obtain [2-(2-hydroxyethyl)piperidino]-N-methyl-N-octadecyl formamide.

Sources & evidence

ORD record
ord-b88c38d452544ee2aee806abd276389e
Source dataset
uspto-grants-2000_05
Patent number
US06057337

Reaction notes

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