反应详情

A mixture of 3-chloro-2,6-dinitrotoluene (18.0 g), cyclohexene (51 mL), and 10% palladium on charcoal (4.5 g) in ethanol (350 mL) was heated at reflux under an atmosphere of nitrogen for 1.5 hr. The reaction mixture was cooled to room temperature, filtered through celite, then evaporated under reduced pressure. The residue was dissolved in ethyl ether and filtered through a short silica column. Evaporation of the ether afforded 14.8 g as an orange solid.

1. temperaturewas heated
2. temperatureat reflux under an atmosphere of nitrogen for 1.5 hr
3. filtrationfiltered through celite
4. customevaporated under reduced pressure
5. dissolutionThe residue was dissolved in ethyl ether
6. filtrationfiltered through a short silica column
7. customEvaporation of the ether
8. customafforded 14.8 g as an orange solid