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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106728Generated: October 30, 2026

2-(3-Aminophenoxy)acetonitrile → Dabuzalgron hydrochloride

https://huagongshe.com/reaction/1106728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Aminophenoxy)acetonitrileHCID 18789699—
ReactantHCID 18789704HCID 18789704—
ReactantHCID 18789725HCID 18789725—
ProductDabuzalgron hydrochlorideHCID 219093—

Reaction Steps

N-[6-chloro-3-(4,5-dihydro-1H-imidazol-2-ylmethoxy)-2-methylphenyl]-methanesulfonamide hydrochloride was prepared from N-(6-chloro-3-cyanomethoxy-2-methylphenyl)-methanesulfonamide in a manner similar to that described in Example 1 for the preparation of N-[3-(4,5-dihydro-1H-imidazol-2-ylmethoxy)phenyl] methanesulfonamide hydrochloride from (3-aminophenoxy)acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06057349
Source datasetuspto-grants-2000_05
ORD IDord-4824439ddd5e40b3b6f21fc1d64c628a
Source noteuspto-grants-2000_05