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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106758Generated: October 31, 2026

N-(3-cyanomethoxyphenyl)methanesulfonamide → N-(3-chloro-5-cyanomethyl-2-methylphenyl) methanesulfonamide

https://huagongshe.com/reaction/1106758

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-cyanomethoxyphenyl)methanesulfonamideHCID 18789601—
Reactant2-(3-Aminophenoxy)acetonitrileHCID 18789699—
Reactant(3-Amino-5-chloro-4-methylphenyl) acetonitrileHCID 54396229—
ProductN-(3-chloro-5-cyanomethyl-2-methylphenyl) methanesulfonamideHCID 53903521—

Reaction Steps

N-(3-chloro-5-cyanomethyl-2-methylphenyl) methanesulfonamide was prepared from (3-amino-5-chloro-4-methylphenyl) acetonitrile in a manner similar to that described in Example 1 for the preparation of N-(3-cyanomethoxyphenyl)-methanesulfonamide from (3-aminophenoxy)-acetonitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06057349
Source datasetuspto-grants-2000_05
ORD IDord-a2c6a46cfcde4a0e9df01dc3b8088c77
Source noteuspto-grants-2000_05