HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 4-[2-(4-(2-phenylethenyl)-3-pyridyl)ethynyl]benzoate → Tert-butyl 4-[2-(4-phenethyl-3-pyridyl)ethyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 4-[2-(4-(2-phenylethenyl)-3-pyridyl)ethynyl]benzoate | HCID 54016878 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran ethanol | HCID 21873804 | — |
| Product | Tert-butyl 4-[2-(4-phenethyl-3-pyridyl)ethyl]benzoate | HCID 22675531 | 97.8% |
Reaction Steps
tert-Butyl 4-[2-(4-(2-phenylethenyl)-3-pyridyl)ethynyl]benzoate (0.360 g, 0.95 mmol) was dissolved in ethanol/THF 1:1 (10 ml) and treated with palladium on carbon (10%, 0.13 g). The reaction was placed under a hydrogen atmosphere and stirred at ambient temperature for 6 hours. The reaction was then filtered and evaporated to give tert-butyl 4-[2-(4-phenethyl-3-pyridyl)ethyl]benzoate (0.36 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06057345 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-b574003c934e453680d746610264ed11 |
| Source note | uspto-grants-2000_05 |