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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106835Generated: October 31, 2026

Tert-butyl 4-[2-(4-(2-phenylethenyl)-3-pyridyl)ethynyl]benzoate → Tert-butyl 4-[2-(4-phenethyl-3-pyridyl)ethyl]benzoate

https://huagongshe.com/reaction/1106835

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 4-[2-(4-(2-phenylethenyl)-3-pyridyl)ethynyl]benzoateHCID 54016878—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuran ethanolHCID 21873804—
ProductTert-butyl 4-[2-(4-phenethyl-3-pyridyl)ethyl]benzoateHCID 2267553197.8%

Reaction Steps

tert-Butyl 4-[2-(4-(2-phenylethenyl)-3-pyridyl)ethynyl]benzoate (0.360 g, 0.95 mmol) was dissolved in ethanol/THF 1:1 (10 ml) and treated with palladium on carbon (10%, 0.13 g). The reaction was placed under a hydrogen atmosphere and stirred at ambient temperature for 6 hours. The reaction was then filtered and evaporated to give tert-butyl 4-[2-(4-phenethyl-3-pyridyl)ethyl]benzoate (0.36 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06057345
Source datasetuspto-grants-2000_05
ORD IDord-b574003c934e453680d746610264ed11
Source noteuspto-grants-2000_05