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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1106840Generated: October 30, 2026

4-[3-(2-Benzylphenyl)prop-1-enyl]benzoic acid → 4-[3-(2-Benzylphenyl)propyl]benzoic acid

https://huagongshe.com/reaction/1106840

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[3-(2-Benzylphenyl)prop-1-enyl]benzoic acidHCID 54402614—
CatalystPalladiumHCID 23938—
SolventTetrahydrofuranHCID 8028—
Product4-[3-(2-Benzylphenyl)propyl]benzoic acidHCID 22675538—

Reaction Steps

A solution of 4-[3-(2-benzylphenyl)prop-1-enyl]benzoic acid (6.43 g) in THF (50 ml) containing 10% palladium on carbon (1 g) was stirred under an atmosphere of hydrogen (balloon) for 15 hours. The catalyst was removed by filtration and the residue obtained on removal of the solvent was purified by chromatography on silica, eluting with 5% methanol in dichloromethane, to give 4-[3-(2-benzylphenyl)propyl]benzoic acid, m.p. 135-6° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06057345
Source datasetuspto-grants-2000_05
ORD IDord-7b32bb356b0640d38b4d8e25ce4e23e8
Source noteuspto-grants-2000_05