HCID 21968255, compound → HCID 53895540, compound

HRID 1106946Notes

Reaction equation

HRID 1106946 reaction equation
[C:1]([N:4]1[C@H:12]([C:13]([O-])=[O:14])[CH2:11][C:10](=[O:16])[C:9]2[CH:17]=[CH:18][CH:19]=[CH:20][C:8]=2[N:7]([CH2:21][C:22]2[CH:27]=[CH:26][C:25]([O:28][CH3:29])=[CH:24][CH:23]=2)[C:6](=[O:30])[C@H:5]1[CH2:31][C:32]12[CH2:41][CH:36]3[CH2:37][CH:38]([CH2:40][CH:34]([CH2:35]3)[CH2:33]1)[CH2:39]2)(=[O:3])[CH3:2].C([N:45]1[C@H:53]([C:54]([O-:56])=[O:55])CC(=O)C2C=CC=CC=2N(CC2C=CC=CC=2)C(=O)[C@H]1CC12CC3CC(CC(C3)C1)C2)(=O)C>>[C:1]([N:4]1[C@H:12]([C:13]([NH:45][CH2:53][C:54]([OH:56])=[O:55])=[O:14])[CH2:11][C:10](=[O:16])[C:9]2[CH:17]=[CH:18][CH:19]=[CH:20][C:8]=2[N:7]([CH2:21][C:22]2[CH:23]=[CH:24][C:25]([O:28][CH3:29])=[CH:26][CH:27]=2)[C:6](=[O:30])[C@H:5]1[CH2:31][C:32]12[CH2:39][CH:38]3[CH2:40][CH:34]([CH2:35][CH:36]([CH2:37]3)[CH2:41]1)[CH2:33]2)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 21968255HCID 21968255, compoundHCID 21968257HCID 21968257, compound

Product 1

HCID 53895540HCID 53895540, compound

Procedure

The compound was prepared by an identical route to that used to prepare example 22 except that (3R,5S)-4-acetyl-3-(1-adamantyl)methyl-1-(4-methoxybenzyl)-2,7-dioxo-2,3,4,5,6,7-hexahydro-1H-1,4-benzodiazonine-5-carboxylate was used in step a in place of (3R,5S)-4-acetyl-3-(1-adamantyl)methyl-1-benzyl-2,7-dioxo-2,3,4,5,6,7-hexahydro-1H-1,4-benzodiazonine-5-carboxylate

Workup

  1. customThe compound was prepared by an identical route to

Sources & evidence

ORD record
ord-74fc83ce5af74c4ea1e693d5298f9e01
Source dataset
uspto-grants-2000_05
Patent number
US06057311

Reaction notes

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