Potassium Carbonate → HCID 18790564, compound

Participants

Reaction Steps

4-[4-[Bis(2-acetoxyethyl)amino]benzylthio]-7-methylthioquinoline (Compound 47; 30 mg, 0.06 mmol) was dissolved in methanol (5 ml) and added with potassium carbonate (34 mg, 0.247 mmol) and stirred at room temperatue for two hours. Methanol was removed under reduced pressure. The reaction mixture was added with water and extracted twice with chloroform. The combined chloroform layers were washed with saturated saline solution. The solvent was removed under reduced pressure and the residue was washed with ethyl acetate to obtain 20 mg of the titled compound (81%).

Provenance & Evidence