HuagongsheHuagongshe Chemistry Print Report · For research reference only
t-Butyl 4-phenyl-2-butenoate → 4-Phenyl-2-butenoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | t-Butyl 4-phenyl-2-butenoate | HCID 53401901 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 4-Phenyl-2-butenoic acid | HCID 53401858 | 99.85% |
Reaction Steps
A solution of 6.3 g (28.86 mmol) of t-butyl 4-phenylbut-2-enoate in 100 mL of CH2Cl2 and 30 mL of trifluoroacetic acid is stirred at 25° C. for 18 hours. The reaction is concentrated in vacuo to afford 4.67 g (99.85%) of 4-phenylbut-2-enoic acid as a yellow crystalline solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06057369 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-6bf6f2351585416a8bfcb7d53d6549df |
| Source note | uspto-grants-2000_05 |