HCID 53688447, compound → HCID 18790086, compound

Participants

Reaction Steps

A solution of ethyl 3-(3,4-dimethoxyphenyl)-7-phenyl-2-heptenoate (0.4 g, 1.1 mmol) in ethanol (20 mL) containing 10% Pd/C (few mg) is stirred under a balloon of hydrogen for 4 hours at room temperature. The catalyst is filtered and the solvent is removed in vacuo to produce ethyl 3-(3,4-dimethoxyphenyl)-7-phenylheptanoate (0.3 g, 73%) as an oil. 1H-NMR (300 MHz, CDCl3) δ (TMS) 1.11-1.20 (t, 3H), 1.20-1.65 (m, 6H), 2.45-2.59 (m, 4H), 2.92-3.10 (m, 1H), 3.82 (s, 6H), 4.00-4.08 (q, 2H), 6.62-6.82 (m, 3H), 7.02-7.28 (m, 5H); MS (EI) m/e 370 (M+).

Provenance & Evidence