Hydrochloric Acid → HCID 18790058, compound

Participants

Reaction Steps

A solution of ethyl 3-(3,4-dimethoxyphenyl)-7-phenylheptanoate (0.3 g, 0.8 mmol) and 10% sodium hydroxide (5 mL) in ethanol (10 mL) is heated under reflux for 30 minutes. The mixture is cooled and is added to aqueous HCl and is extracted with ether. The organic layer is washed with water and is dried over MgSO4. The solvent is removed in vacuo to afford 3-(3,4-dimethoxyphenyl)-7-phenylheptanoic acid (0.25 g, 92%); MS (EI) m/e 342 (M+).

Provenance & Evidence