Ethanol → HCID 70294261, compound

Participants

Reaction Steps

The above ester (5.4 g, 12.1 mmol) was dissolved in ethanol (50 ml), 5 N sodium hydroxide (5 ml) was added, and the mixture was stirred at room temperature for 20 h. Ethanol was evaporated in vacuo, water (50 ml) and acetic acid (7 ml) were added, and the mixture was extracted with dichloromethane (100 ml). The organic phase was dried (MgSO4) and the solvent was evaporated in vacuo. The residue was dissolved in acetone and treated with oxalic acid to give 3.8 g (62%) of the title compound.

Provenance & Evidence