HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-(2-Propoxybenzamido)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Amino-3-pyridinecarboxamide | HCID 13498082 | — |
| Reactant | 2-Propoxybenzoyl chloride | HCID 15921913 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4-(2-Propoxybenzamido)nicotinamide | HCID 22462387 | — |
Reaction Steps
In a similar manner to Example 68 a) reaction of 2-propoxybenzoyl chloride (0.79 g), 4-aminonicotinamide (0.55 g) and triethylamine (0.40 g) in acetonitrile (12 ml) afforded a crude product which was recrystallized from ethanol-ether to afford 4-(2-propoxybenzamido)nicotinamide, 0.53 g, m.p. 164-166° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06060477 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-0cd95280b0984d7ea1ab4933341adc23 |
| Source note | uspto-grants-2000_05 |