HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetonitrile → Phenyl(pyridin-3-yl)acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetonitrile | HCID 8794 | — |
| Reactant | 3-Chloropyridine | HCID 12287 | — |
| Reactant | Potassium tert-butoxide | HCID 23665647 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Phenyl(pyridin-3-yl)acetonitrile | HCID 270956 | — |
Reaction Steps
The compound was prepared substantially in accordance with the procedure in Example 12A, using 3-chloropyridine (9.5 ml, 100 mmol), benzyl cyanide (11.6 ml, 100 mmol) and potassium t-butoxide (22.4 g, 200 mmol) in 200 ml of DMF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06060484 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-812c456818834fe4a33fa148a127b9cc |
| Source note | uspto-grants-2000_05 |