1-Iodohexane → HCID 54079891, compound

HRID 1107567Notes

Reaction equation

HRID 1107567 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][OH:8])[CH2:2]1.I[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]>>[CH2:10]([N:1]1[CH2:6][CH2:5][CH2:4][CH:3]([CH2:7][OH:8])[CH2:2]1)[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 125271-IodohexaneHCID 107308Piperidin-3-ylmethanol

Product 1

HCID 54079891HCID 54079891, compoundYield 93.6%

Procedure

3-Piperidine methanol (2.30 g, 20 mmol) and 1-iodohexane (1.5 mL, 10 mmol) were converted to product by the procedure of Preparation 1 to yield 1.866 g (47%) of the title compound which was used without further purification. 1H NMR consistent with desired product.

Sources & evidence

ORD record
ord-671227046b544e8db1ecb60431837eb8
Source dataset
uspto-grants-2000_05
Patent number
US06060488

Reaction notes

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