4-Fluorobenzylic alcohol → HCID 18785670, compound

HRID 1107741Notes

Reaction equation

HRID 1107741 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]=[CH2:15])[C:7]=12.[F:16][C:17]1[CH:24]=[CH:23][C:20]([CH2:21][OH:22])=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:24]=[CH:23][C:20]([CH2:21][O:22][C:2]2[N:3]=[N:4][CH:5]=[C:6]3[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]=[CH2:15])[C:7]=23)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 680224-Fluorobenzylic alcoholHCID 18785586HCID 18785586, compound

Product 1

HCID 18785670HCID 18785670, compoundYield 22.1%

Procedure

The title compound was prepared as a white powder in 22.1% yield in a similar procedure to that described in Example 1 by using 7-chloro-2,3-dimethyl-1-(2-propenyl)pyrrolo[2,3-d]pyridazine and 4-fluorobenzyl alcohol.

Sources & evidence

ORD record
ord-a3958ac3bb7b46c49f0cb12052f7e6b7
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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