3-Fluorobenzylic alcohol → HCID 18785664, compound

HRID 1107742Notes

Reaction equation

HRID 1107742 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]=[CH2:15])[C:7]=12.[F:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH2:20][OH:21]>>[F:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][CH:24]=1)[CH2:20][O:21][C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]=[CH2:15])[C:7]=12

Participants

3

Reactant 2

HCID 680083-Fluorobenzylic alcoholHCID 18785586HCID 18785586, compound

Product 1

HCID 18785664HCID 18785664, compoundYield 71.4%

Procedure

The title compound was prepared as white cottony crystals in 71.4% yield in a similar procedure to that described in Example 1 by using 7-chloro-2,3-dimethyl-1-(2-propenyl)pyrrolo[2,3-d]pyridazine and 3-fluorobenzyl alcohol.

Sources & evidence

ORD record
ord-bb0990f81b664ac69bb27311876e107b
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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