2,4-Difluorobenzyl alcohol → HCID 18785702, compound

HRID 1107743Notes

Reaction equation

HRID 1107743 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]=[CH2:15])[C:7]=12.[F:16][C:17]1[CH:24]=[C:23]([F:25])[CH:22]=[CH:21][C:18]=1[CH2:19][OH:20]>>[F:16][C:17]1[CH:24]=[C:23]([F:25])[CH:22]=[CH:21][C:18]=1[CH2:19][O:20][C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]=[CH2:15])[C:7]=12

Participants

3

Reactant 2

HCID 918672,4-Difluorobenzyl alcoholHCID 18785586HCID 18785586, compound

Product 1

HCID 18785702HCID 18785702, compoundYield 26.6%

Procedure

The title compound was prepared as a white powder in 26.6% yield in a similar procedure to that described in Example 1 by using 7-chloro-2,3-dimethyl-1-(2-propenyl)pyrrolo[2,3-d]pyridazine and 2,4-difluorobenzyl alcohol.

Sources & evidence

ORD record
ord-c7287f3a7c1b4b67904bad083fbcff99
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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