Benzyl Alcohol → HCID 15888182, compound

HRID 1107746Notes

Reaction equation

HRID 1107746 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][C:14]([F:17])([F:16])[F:15])[C:7]=12.[CH2:18]([OH:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:18]([O:25][C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][C:14]([F:17])([F:16])[F:15])[C:7]=12)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 18785708HCID 18785708, compound

Product 1

HCID 15888182HCID 15888182, compoundYield 65.2%

Procedure

The title compound was prepared as a white powder in 65.20% yield in a similar procedure to that described in Example 1 by using 7-chloro-2,3-dimethyl-1-(2,2,2-trifluoroethyl)pyrrolo[2,3-d]pyridazine and benzyl alcohol.

Sources & evidence

ORD record
ord-d2f227ff992b4af596b2417512620828
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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