2,4-Dichlorobenzyl alcohol → HCID 18785726, compound

HRID 1107748Notes

Reaction equation

HRID 1107748 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]=[CH2:15])[C:7]=12.[Cl:16][C:17]1[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:18]=1[CH2:19][OH:20]>>[Cl:16][C:17]1[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:18]=1[CH2:19][O:20][C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]=[CH2:15])[C:7]=12

Participants

3

Reactant 2

HCID 156842,4-Dichlorobenzyl alcoholHCID 18785586HCID 18785586, compound

Product 1

HCID 18785726HCID 18785726, compoundYield 76.5%

Procedure

The title compound was prepared as white crystals in 76.5% yield in a similar procedure to that described in Example 1 by using 7-chloro-2,3-dimethyl-1-(2-propenyl)pyrrolo[2,3-d]pyridazine and 2,4-dichlorobenzyl alcohol.

Sources & evidence

ORD record
ord-27aa841d88044a529ead07083bb30b93
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

Loading…