Benzyl Alcohol → HCID 15888186, compound

HRID 1107750Notes

Reaction equation

HRID 1107750 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH2:14][CH2:15][F:16])[C:7]=12.[CH2:17]([OH:24])[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[CH2:17]([O:24][C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH2:14][CH2:15][F:16])[C:7]=12)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 18785662HCID 18785662, compound

Product 1

HCID 15888186HCID 15888186, compoundYield 71.2%

Procedure

The title compound was prepared as white crystals in 71.2% yield in a similar procedure to that described in Example 1 by using 7-chloro-1-(3-fluoropropyl)-2,3-dimethylpyrrolo[2,3-d]pyridazine and benzyl alcohol.

Sources & evidence

ORD record
ord-afc852755e40416aa3bee4087e83dbf7
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

Loading…