4-Fluorobenzylic alcohol → HCID 18785684, compound

HRID 1107757Notes

Reaction equation

HRID 1107757 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][C:14]([CH3:16])=[CH2:15])[C:7]=12.[F:17][C:18]1[CH:25]=[CH:24][C:21]([CH2:22][OH:23])=[CH:20][CH:19]=1>>[F:17][C:18]1[CH:25]=[CH:24][C:21]([CH2:22][O:23][C:2]2[N:3]=[N:4][CH:5]=[C:6]3[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][C:14]([CH3:16])=[CH2:15])[C:7]=23)=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 680224-Fluorobenzylic alcoholHCID 18785658HCID 18785658, compound

Product 1

HCID 18785684HCID 18785684, compoundYield 38.7%

Procedure

The title compound was prepared as a grayish white powder in 38.7% yield in a similar procedure to that described in Example 1 by using 7-chloro-2,3-dimethyl-1-(2-methyl-2-propenyl)pyrrolo[2,3-d]pyridazine and 4-fluorobenzyl alcohol.

Sources & evidence

ORD record
ord-c9a45f3a52814327927a40b2669ee6ad
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

Loading…