HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzylic alcohol → 1-(2-Butenyl)-7-(4-fluorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzylic alcohol | HCID 68022 | — |
| Reactant | 1-(2-Butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine | HCID 53719624 | — |
| Product | 1-(2-Butenyl)-7-(4-fluorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazine | HCID 53996954 | 59.3% |
Reaction Steps
The title compound (cis/trans=98/2) was prepared as pale brown crystals in 59.3% yield in a similar procedure to that described in. Example 1 by using 1-(2-butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine (cis/trans=94/6) and 4-fluorobenzyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06063782 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-22e0201958ff4fc5b27145f6886edb76 |
| Source note | uspto-grants-2000_05 |