4-Fluorobenzylic alcohol → HCID 15888194, compound

HRID 1107765Notes

Reaction equation

HRID 1107765 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][CH:14]3[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]3)[C:7]=12.[F:20][C:21]1[CH:28]=[CH:27][C:24]([CH2:25][OH:26])=[CH:23][CH:22]=1>>[CH:14]1([CH2:13][N:8]2[C:7]3=[C:2]([O:26][CH2:25][C:24]4[CH:27]=[CH:28][C:21]([F:20])=[CH:22][CH:23]=4)[N:3]=[N:4][CH:5]=[C:6]3[C:10]([CH3:11])=[C:9]2[CH3:12])[CH2:19][CH2:18][CH2:17][CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 680224-Fluorobenzylic alcoholHCID 18785689HCID 18785689, compound

Product 1

HCID 15888194HCID 15888194, compoundYield 45.6%

Procedure

The title compound was prepared as a white powder in 45.6% yield in a similar procedure to that described in Example 1 by using 7-chloro-1-cyclohexylmethyl-2,3-dimethylpyrrolo[2,3-d]pyridazine and 4-fluorobenzyl alcohol.

Sources & evidence

ORD record
ord-083a141cd1a84cb19cc64b4d4c09a69c
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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