HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-6-fluorobenzyl alcohol → 1-(2-Butenyl)-7-(2-chloro-6-fluorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-6-fluorobenzyl alcohol | HCID 91868 | — |
| Reactant | 1-(2-Butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine | HCID 53719624 | — |
| Product | 1-(2-Butenyl)-7-(2-chloro-6-fluorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazine | HCID 53716849 | 57.6% |
Reaction Steps
The title compound (cis/trans=21/79) was prepared as a pale brown powder in 57.60% yield in a similar procedure to that described in Example 1 by using 1-(2-butenyl)-7-chloro-2,3-dimethylpyrrolo[2,3-d]pyridazine (cis/trans=24/76) and 2-chloro-6-fluorobenzyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06063782 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-b399ab50b4964b8d832710991b0613ed |
| Source note | uspto-grants-2000_05 |