1,3-Dichloropropene → HCID 54039476, compound

HRID 1107771Notes

Reaction equation

HRID 1107771 reaction equation
[F:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][O:7][C:8]2[N:9]=[N:10][CH:11]=[C:12]3[C:16]([CH3:17])=[C:15]([CH3:18])[NH:14][C:13]=23)=[CH:4][CH:3]=1.[Cl:21][CH:22]=[CH:23][CH2:24]Cl>>[Cl:21][CH:22]=[CH:23][CH2:24][N:14]1[C:13]2=[C:8]([O:7][CH2:6][C:5]3[CH:19]=[CH:20][C:2]([F:1])=[CH:3][CH:4]=3)[N:9]=[N:10][CH:11]=[C:12]2[C:16]([CH3:17])=[C:15]1[CH3:18]

Participants

3

Reactant 2

HCID 248831,3-DichloropropeneHCID 18785739HCID 18785739, compound

Product 1

HCID 54039476HCID 54039476, compoundYield 31.4%

Procedure

The title compound (cis/trans=1/1) was prepared as a pale yellow powder in 31.4% yield in a similar procedure to that described in Example 41 by using 7-(4-fluorobenzyloxy)-2,3-dimethylpyrrolo[2,3-d]pyridazine and 1,3-dichloropropene (a mixture of cis and trans isomers).

Workup

  1. additiona mixture of cis and trans isomers)

Sources & evidence

ORD record
ord-f56425dd59e3402595504823e7aa27d1
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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