Benzyl Alcohol → HCID 18785665, compound

HRID 1107773Notes

Reaction equation

HRID 1107773 reaction equation
Cl[C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH2:13][C:14]#[CH:15])[C:7]=12.[CH2:16]([OH:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([O:23][C:2]1[N:3]=[N:4][CH:5]=[C:6]2[C:10]([CH3:11])=[C:9]([CH3:12])[N:8]([CH:13]=[C:14]=[CH2:15])[C:7]=12)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 244Benzyl AlcoholHCID 18785647HCID 18785647, compound

Product 1

HCID 18785665HCID 18785665, compoundYield 37.6%

Procedure

The title compound was prepared as pale brown crystals in 37.6% yield in a similar procedure to that described in Example 44 by using 7-chloro-2,3-dimethyl-1-(2-propynyl)pyrrolo[2,3-d]pyridazine and benzyl alcohol.

Sources & evidence

ORD record
ord-b5559fad3a41411f805bf3a282618833
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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