3-bromo-3,3-difluoroprop-1-ene → HCID 18785680, compound
Reaction equation
[CH:1]([C:3]1[C:7]([CH3:8])=[C:6]([CH3:9])[NH:5][C:4]=1[C:10]([O:12][CH3:13])=[O:11])=[O:2].Br[C:15]([F:19])([F:18])[CH:16]=[CH2:17]>>[F:18][C:15]([F:19])=[CH:16][CH2:17][N:5]1[C:6]([CH3:9])=[C:7]([CH3:8])[C:3]([CH:1]=[O:2])=[C:4]1[C:10]([O:12][CH3:13])=[O:11]Participants
3
Procedure
The title compound was prepared as a pale yellow oil in 70.4% yeild in a similar procedure to that described in Referential Example 9 by using methyl 3-formyl-4,5-dimethylpyrrole-2-carboxylate and 3-bromo-3,3-difluoro-1-propene.
Sources & evidence
- ORD record
- ord-fe30e05d15c94713a00bcb747c3d1a2d
- Source dataset
- uspto-grants-2000_05
- Patent number
- US06063782
Reaction notes
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