2-Butene, 1-bromo- → HCID 53660002, compound

HRID 1107823Notes

Reaction equation

HRID 1107823 reaction equation
[CH3:1][C:2]1[NH:3][C:4]([C:8](=[O:17])[CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][C:6]=1[CH3:7].Br[CH2:19][CH:20]=[CH:21][CH3:22]>>[CH2:19]([N:3]1[C:4]([C:8](=[O:17])[CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][C:6]([CH3:7])=[C:2]1[CH3:1])[CH:20]=[CH:21][CH3:22]

Participants

3

Reactant 2

HCID 1224142-Butene, 1-bromo-HCID 18785604HCID 18785604, compound

Product 1

HCID 53660002HCID 53660002, compoundYield 75.7%

Procedure

The title compound (cis/trans=23/77) was prepared as a yellow oil in 75.7% yield in a similar procedure to that described in Referential Example 97 by using 2,3-dimethyl-5-(3-phenylpropionyl)pyrrole and 1-bromo-2-butene.

Sources & evidence

ORD record
ord-0c5ff82e5111466aa2794bee5378088f
Source dataset
uspto-grants-2000_05
Patent number
US06063782

Reaction notes

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