HCID 18785604, compound → HCID 18785727, compound
Reaction equation
[CH3:1][C:2]1[NH:3][C:4]([C:8](=[O:17])[CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][C:6]=1[CH3:7].Br[CH2:19][CH:20]1[CH2:22][CH:21]1[CH3:23]>>[CH3:1][C:2]1[N:3]([CH2:19][CH:20]2[CH2:22][CH:21]2[CH3:23])[C:4]([C:8](=[O:17])[CH2:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:5][C:6]=1[CH3:7]Participants
3
Procedure
The title compound was prepared as a yellow oil in 99.1% yield in a similar procedure to that described in Referential Example 97 by using 2,3-dimethyl-5-(3-phenylpropionyl)pyrrole and 1-bromomethyl-2-methylcyclopropane.
Sources & evidence
- ORD record
- ord-b3f024e0e4ff42d88e31c7859e11dcc3
- Source dataset
- uspto-grants-2000_05
- Patent number
- US06063782
Reaction notes
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