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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1108061Generated: October 31, 2026

CJ-13454 → 1-[5-Fluoro-3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]cyclopentane-1-carboxamide

https://huagongshe.com/reaction/1108061

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCJ-13454HCID 9931329—
ReactantEthyl 1-[3-fluoro-5-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]cyclopentane-1-carboxylateHCID 18786351—
Product1-[5-Fluoro-3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]cyclopentane-1-carboxamideHCID 9800723—

Reaction Steps

The desired compound was prepared from ethyl 1-[3-fluoro-5-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]cyclopentane-1-carboxylate according to the preparation of 4-[5-fluoro-3-[4-(2-methylimidazol-1-yl)benzyloxy]phenyl]-3,4,5,6-tetrahydro-2H-pyran-4-carboxamide (Example 5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06063928
Source datasetuspto-grants-2000_05
ORD IDord-cbe821a45e75430891ed1782031d8de9
Source noteuspto-grants-2000_05