Pyrrolidine → HCID 69949854, compound

Participants

Reaction Steps

A solution of an ethanol (5 mL) solution of a 6-(benzoylamino)-3,4-epoxy-3,4-dihydro-2,2-dimethyl-7-nitro-2H-1-benzopyran (II-1) (147 mg, 0.43 mmol) was added with a pyrrolidine (0.07 mL) and heated under reflux for two hours. After the mixture was cooled to room temperature, the mixture was concentrated and the obtained residue was purified through silica gel column chromatography (hexane:ethyl acetate=3:1) to obtain the intended product (40.3 mg, 23%) as a brown solid.

Provenance & Evidence