Methane → HCID 15462259, compound

Participants

Reaction Steps

6-Amino-1-(4-chlorobenzyl)-5-formylamino-uracil (25.58 g) in 200 ml of 2N NaOH and 150 ml of water was heated under reflux for 3 hours. Charcoal (2.6 g) was added, and after filtration the solution was neutralized to pH 7.0 and the solid collected. Reprecipitation from NaOH by neutralization with HCl gave 22.91 g of title compound as a white solid mp 304-10° C.

Provenance & Evidence