N-bromobutanimide → 4-Bromo-2-(cyclopropyl-methoxy-methyl)-7-methoxybenzofuran

HRID 1108304Notes

Reaction equation

HRID 1108304 reaction equation
[CH:1]1([CH:4]([O:16][CH3:17])[C:5]2[O:6][C:7]3[C:13]([O:14][CH3:15])=[CH:12][CH:11]=[CH:10][C:8]=3[CH:9]=2)[CH2:3][CH2:2]1.[Br:18]N1C(=O)CCC1=O>C(#N)C>[Br:18][C:10]1[C:8]2[CH:9]=[C:5]([CH:4]([CH:1]3[CH2:2][CH2:3]3)[O:16][CH3:17])[O:6][C:7]=2[C:13]([O:14][CH3:15])=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 187848602-(Cyclopropyl-methoxy-methyl)-7-methoxybenzofuran

Product 1

HCID 187848654-Bromo-2-(cyclopropyl-methoxy-methyl)-7-methoxybenzofuran

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Prepared from 2-(cyclopropyl-methoxy-methyl)-7-methoxybenzofuran (3.12 g) and N-bromosuccinimide (2.4 g) in acetonitrile (45 ml). The title compound was obtained as an orange gum (3.49 g).

Sources & evidence

ORD record
ord-2473bdb5fa6842c9a7311ed7a2b9ade3
Source dataset
uspto-grants-2000_05
Patent number
US06066657

Reaction notes

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