HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrophenol → HCID 53939334, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrophenol | HCID 980 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | HCID 18784851 | HCID 18784851 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | HCID 53939334 | HCID 53939334 | 86.9% |
Reaction Steps
Prepared from 2-dimethylsulfamyl-7-methoxybenzofuran-4-carboxylic acid (0.5 g), 4-nitrophenol (270 mg), 4-dimethylaminopyridine (11 mg) and 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (370 mg) in dichloromethane (30 ml). Trituration from ethyl acetate and hexane afforded the desired product as a cream solid (0.61 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06066657 |
| Source dataset | uspto-grants-2000_05 |
| ORD ID | ord-c11396f68bb24090aa46e6fdf96fc20f |
| Source note | uspto-grants-2000_05 |