Propionyl chloride → HCID 22627152, compound

HRID 1108689Notes

Reaction equation

[CH2:1]([C:3]1[C:11]2[C:6](=[CH:7][C:8]([C:12]([O:14][CH3:15])=[O:13])=[CH:9][CH:10]=2)[NH:5][CH:4]=1)[CH3:2].[C:16](Cl)(=[O:19])[CH2:17][CH3:18]>>[CH2:1]([C:3]1[C:11]2[C:6](=[CH:7][C:8]([C:12]([O:14][CH3:15])=[O:13])=[CH:9][CH:10]=2)[NH:5][C:4]=1[C:16](=[O:19])[CH2:17][CH3:18])[CH3:2]

Participants

Reactant 2

HCID 62324Propionyl chloride

HCID 22627226HCID 22627226, compound

Product 1

HCID 22627152HCID 22627152, compound

Procedure

Methyl 3-ethyl-2-propionylindole-6-carboxylate (65.7 mg) was prepared from methyl 3-ethylindole-6-carboxylate (184 mg) and propionyl chloride (0.17 ml) in a similar manner to that of Preparation 1 (5).

Sources & evidence

ORD record: ord-4693aa1ba4504aa583fb94f6606e605d
Source dataset: uspto-grants-2000_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06069156

Reaction notes

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