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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1108720Generated: October 30, 2026

alpha-Bromo-o-chlorotoluene → Methyl 1-(2-chlorobenzyl)-2-isobutyl-3-isobutyrylindole-6-carboxylate

https://huagongshe.com/reaction/1108720

Reaction equation

Participants

RoleNameHCIDCharge
Reactantalpha-Bromo-o-chlorotolueneHCID 11905—
ReactantMethyl 2-isobutyl-3-isobutyrylindole-6-carboxylateHCID 22627171—
ProductMethyl 1-(2-chlorobenzyl)-2-isobutyl-3-isobutyrylindole-6-carboxylateHCID 2262734386.9%

Reaction Steps

Methyl 1-(2-chlorobenzyl)-2-isobutyl-3-isobutyrylindole -6-carboxylate (258 mg) was prepared from methyl 2-isobutyl-3-isobutyrylindole-6-carboxylate (210 mg) and 2-chlorobenzyl bromide (157 mg) in a similar manner to that of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06069156
Source datasetuspto-grants-2000_05
ORD IDord-890faa65b90a415aa2934d4b2e8d4054
Source noteuspto-grants-2000_05