N-bromobutanimide → HCID 9937303, compound

HRID 1108829Notes

Reaction equation

HRID 1108829 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[C:12]([Cl:13])=[CH:11][C:10]([C:14]([F:17])([F:16])[F:15])=[CH:9][C:8]=2[Cl:18])[N:5]=[C:4]([C:19]#[N:20])[C:3]=1[C:21]1[O:25][N:24]=[C:23]([Br:26])[CH:22]=1.[Br:27]N1C(=O)CCC1=O>C(#N)C>[NH2:1][C:2]1[N:6]([C:7]2[C:12]([Cl:13])=[CH:11][C:10]([C:14]([F:17])([F:15])[F:16])=[CH:9][C:8]=2[Cl:18])[N:5]=[C:4]([C:19]#[N:20])[C:3]=1[C:21]1[O:25][N:24]=[C:23]([Br:26])[C:22]=1[Br:27]

Participants

4

Reactant 2

HCID 67184N-bromobutanimideHCID 9934269HCID 9934269, compound

Product 1

HCID 9937303HCID 9937303, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

To a solution of 5-amino-4-(3-bromoisoxazol-5-yl)-3-cyano-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole (0.05 g) in acetonitrile (6 ml) was added N-bromosuccinimide (0.02 g). The mixture was left at room temperature for 24 hours during which time a precipitate formed which was isolated by filtration. Washing with methanol, followed by drying, afforded the title compound as a white solid, m.p. 279° C.

Workup

  1. customformed which
  2. customwas isolated by filtration
  3. washWashing with methanol
  4. customby drying

Sources & evidence

ORD record
ord-3aed6c53194542b89895dc157d5e031a
Source dataset
uspto-grants-2000_05
Patent number
US06069157

Reaction notes

Loading…