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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1108984Generated: October 31, 2026

(Hexahydro-1H-pyrrolizin-7A-YL)methanamine → HCID 9817324, compound

https://huagongshe.com/reaction/1108984

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Hexahydro-1H-pyrrolizin-7A-YL)methanamineHCID 10654304—
ReactantHCID 86747893HCID 86747893—
SolventTolueneHCID 1140—
ProductHCID 9817324HCID 9817324—

Reaction Steps

7a-Aminomethylhexahydro-1H-pyrrolizine is reacted with indoline-N-trichloromethylcarbamate [J. Medicinal Chemistry (1990) 33: 1929] in toluene at reflux to afford the title compound after extractive workup and column chromatography.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05318977
Source datasetuspto-grants-1994_06
ORD IDord-32121799e1a64314b1f362773e37ef60
Source noteuspto-grants-1994_06