6639-66-3 → HCID 15227806, compound

HRID 1108992Notes

Reaction equation

HRID 1108992 reaction equation
C([O:8][C:9]1[C:17]([O:18][CH3:19])=[CH:16][CH:15]=[C:14]2[C:10]=1[CH2:11][CH2:12][C:13]2=O)C1C=CC=CC=1.CC1C=CC(N=[CH:29][C:30]2[C:31]([NH2:39])=[CH:32][C:33]3[O:37][CH2:36][O:35][C:34]=3[CH:38]=2)=CC=1>>[CH3:19][O:18][C:17]1[CH:16]=[CH:15][C:14]2[C:13]3=[N:39][C:31]4[CH:32]=[C:33]5[O:37][CH2:36][O:35][C:34]5=[CH:38][C:30]=4[CH:29]=[C:12]3[CH2:11][C:10]=2[C:9]=1[OH:8]

Participants

3

Reactant 2

HCID 2416176639-66-3HCID 19021694HCID 19021694, compound

Product 1

HCID 15227806HCID 15227806, compoundYield 50.1%

Procedure

Using the procedure of Example 1, 4-benzoxy-5-methoxyindan-1-one (mg, 2 mmol) is reacted with 6[[(4-methylphenyl)imino]methyl]-1,3-benzodioxol-5-amine (510 mg, 2 mmol) to yields 8-methoxy-9-hydroxy-10H-1,3-dioxolo[4,5-g]indeno[1,2-b]quinoline (308 mg, 38.7% of theory) which is used as a starting material for part (B).

Sources & evidence

ORD record
ord-662da9f99f194e518ec4d714075364b3
Source dataset
uspto-grants-1994_06
Patent number
US05318976

Reaction notes

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