3-Bromo-n-(2-methoxyethyl)benzenesulfonamide → N-(2-Methoxy-ethyl)-3-[7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-benzenesulfonamide

HRID 110921Notes

Reaction equation

HRID 110921 reaction equation
[Br:26][c:27]1[cH:28][c:29]([S:33](=[O:34])(=[O:35])[NH:36][CH2:37][CH2:38][O:39][CH3:40])[cH:30][cH:31][cH:32]1.[C:1](#[CH:2])[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]>>[C:1](#[C:2][c:27]1[cH:28][c:29]([S:33](=[O:34])(=[O:35])[NH:36][CH2:37][CH2:38][O:39][CH3:40])[cH:30][cH:31][cH:32]1)[c:3]1[cH:4][n:5][n:6]2[c:7]1[n:8][c:9](-[c:16]1[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]1)[cH:10][c:11]2[C:12]([F:13])([F:14])[F:15]

Participants

3

Reactant 2

HCID 471084603-Bromo-n-(2-methoxyethyl)benzenesulfonamideHCID 715397323-Ethynyl-7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 86608072N-(2-Methoxy-ethyl)-3-[7-trifluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-benzenesulfonamide

Sources & evidence

ORD record
ord-aeafcac750bd4a6a85ece7ef5454b7fe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

Loading…