5-bromo-3-(5-(1-ethylazetidin-3-yl)pyridin-2-ylamino)-1-methylpyridin-2(1H)-one → 2-(5-(5-(1-Ethylazetidin-3-yl)pyridin-2-ylamino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-4-fluoro-6-(1-oxo-3,4,6,7,8,9-hexahydropyrazino[1,2-a]indol-2(1H)-yl)benzyl Acetate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([CH:17]3[CH2:18][N:19]([CH2:21][CH3:22])[CH2:20]3)[cH:15][cH:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1.[C:23]([CH3:24])(=[O:25])[O:26][CH2:27][c:28]1[c:29]([B:49]2[O:50][C:51]([CH3:52])([CH3:53])[C:54]([CH3:55])([CH3:56])[O:57]2)[cH:30][c:31]([F:48])[cH:32][c:33]1[N:34]1[C:35](=[O:47])[c:36]2[n:37]([c:38]3[c:43]([cH:44]2)[CH2:42][CH2:41][CH2:40][CH2:39]3)[CH2:45][CH2:46]1>>[c:2]1(-[c:29]2[c:28]([CH2:27][O:26][C:23]([CH3:24])=[O:25])[c:33]([N:34]3[C:35](=[O:47])[c:36]4[n:37]([c:38]5[c:43]([cH:44]4)[CH2:42][CH2:41][CH2:40][CH2:39]5)[CH2:45][CH2:46]3)[cH:32][c:31]([F:48])[cH:30]2)[cH:3][c:4]([NH:10][c:11]2[n:12][cH:13][c:14]([CH:17]3[CH2:18][N:19]([CH2:21][CH3:22])[CH2:20]3)[cH:15][cH:16]2)[c:5](=[O:9])[n:6]([CH3:8])[cH:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-df6f1407f65a41a19d1710d992bdb391
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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