(2,4,6-Trichlorophenyl)hydrazine → HCID 2805560, compound

HRID 1109446Notes

Reaction equation

HRID 1109446 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[C:3]=1[NH:10][NH2:11].CN([CH:15]=[C:16]([C:22]([CH3:24])=O)[C:17]([O:19][CH2:20][CH3:21])=[O:18])C>C(O)C>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[C:3]=1[N:10]1[C:22]([CH3:24])=[C:16]([C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:15]=[N:11]1

Participants

4

Reactant 2

HCID 79234(2,4,6-Trichlorophenyl)hydrazineHCID 3806790Ethyl 2-acetyl-3-(dimethylamino)acrylate

Product 1

HCID 2805560HCID 2805560, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

By the method of Example 3, Step C, 25.9 g (0.122 mole) of 2,4,6-trichlorophenylhydrazine and 22.7 g (0.123 mole) of ethyl 2-dimethylaminomethyleneacetoacetate were reacted in ethanol, yielding 1-(2,4,6-trichlorophenyl)-4-ethoxycarbonyl-5-methyl-1H-pyrazole as tan solid; mp 112.5°-113° C. The NMR spectrum was consistent with the proposed structure.

Sources & evidence

ORD record
ord-e10ec31b0c4f4d4892b9a6a45c432178
Source dataset
uspto-grants-1994_06
Patent number
US05321002

Reaction notes

Loading…