Pyridine → HCID 67822846, compound

HRID 1109449Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[C:3]=1[N:10]1[C:14]([CH2:15][Br:16])=[C:13]([C:17]#[N:18])[CH:12]=[N:11]1.[N:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[Br-:16].[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[C:4]([Cl:9])[C:3]=1[N:10]1[C:14]([CH2:15][N+:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[C:13]([C:17]#[N:18])[CH:12]=[N:11]1

Participants

Reactant 2

HCID 1049Pyridine

HCID 19020317HCID 19020317, compound

Product 1

HCID 67822846HCID 67822846, compound

Procedure

The method of Example 1, Step G, using 20.7 g of the mixture from Step D above dissolved in 90 mL of warm pyridine, yielded 11.1 g of N-[1-(2,4,6-trichlorophenyl)-4-cyano-1H-pyrazol-5-ylmethyl]pyridinium bromide, which was used without further purification in Step F.

Sources & evidence

ORD record: ord-08f688858e7a441bba75c8139ec966d6
Source dataset: uspto-grants-1994_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05321002

Reaction notes

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