HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → Prop-2-en-1-yl 3-(pyrrolidin-1-yl)but-2-enoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | Allyl acetoacetate | HCID 70701 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | Prop-2-en-1-yl 3-(pyrrolidin-1-yl)but-2-enoate | HCID 54524772 | 46.1% |
Reaction Steps
Allyl acetoacetate (68.4 ml, 0.5 mol) was added to pyrrolidine (41.6 ml, 0.5 mol) in 150 ml of toluene. An exotherm was noted. The mixture was heated at reflux for 3 hours, cooled, and stripped of toluene to yield 45 g of title product as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05321020 |
| Source dataset | uspto-grants-1994_06 |
| ORD ID | ord-c99f0792fdc242faa701d85b2754e09c |
| Source note | uspto-grants-1994_06 |