HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 18652324, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | HCID 18652326 | HCID 18652326 | — |
| Product | HCID 18652324 | HCID 18652324 | 42% |
Reaction Steps
Using a similar procedure to that described in Example 16, (R)-(-)-4-[5-fluoro-3-(2-methyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-7-ylthio)phenyl]-4-methoxytetrahydropyran was reacted with methyl iodide to give (R)-(-)-4-[5-fluoro-3-(2,4-dimethyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-7-ylthio)phenyl]-4-methoxytetrahydropyran in 42% yield, m.p. 107°-109° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05321025 |
| Source dataset | uspto-grants-1994_06 |
| ORD ID | ord-dc69cc75732941e88e26cb3de20b49c8 |
| Source note | uspto-grants-1994_06 |