HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[2-(4-Chlorophenyl)ethyl]piperazine → HCID 19020602, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[2-(4-Chlorophenyl)ethyl]piperazine | HCID 12235714 | — |
| Reactant | 3-Bromo-4-nitrobenzoic acid | HCID 16218087 | — |
| Reactant | HCID 19020626 | HCID 19020626 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | HCID 19020602 | HCID 19020602 | — |
Reaction Steps
In a manner analogous to that described in Example 2, 1-(4-nitro-3-bromobenzoyl)-4-[2-(4-chlorophenyl)ethyl]-piperazine is prepared from 4.7 g of 4-nitro-3-bromobenzoic acid and 1-[2-(4-chlorophenyl)ethyl]-piperazine and, as described in Example 3, reduced in the presence of Raney nickel to form 1-(4-amino-3-bromobenzoyl)-4-[2-(4-chlorophenyl)ethyl]-piperazine having a melting point of 120°-123°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05321027 |
| Source dataset | uspto-grants-1994_06 |
| ORD ID | ord-e3ed9034874e41a7ae3850c43c4002af |
| Source note | uspto-grants-1994_06 |