Chloroacetone → HCID 19020653, compound

HRID 1109488Notes

Reaction equation

HRID 1109488 reaction equation
[CH:1]1([CH2:7][N:8]2[C:17](=[O:18])[C:16]3[NH:15][CH:14]=[N:13][C:12]=3[N:11]([CH2:19][CH:20]3[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]3)[C:9]2=[O:10])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl[CH2:27][C:28](=[O:30])[CH3:29]>>[CH:1]1([CH2:7][N:8]2[C:17](=[O:18])[C:16]3[N:15]([CH2:27][C:28](=[O:30])[CH3:29])[CH:14]=[N:13][C:12]=3[N:11]([CH2:19][CH:20]3[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]3)[C:9]2=[O:10])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 6571ChloroacetoneHCID 23168008HCID 23168008, compound

Product 1

HCID 19020653HCID 19020653, compound

Procedure

1,3-Di-cyclohexylmethyl-7-(2-oxopropyl)-xanthine was prepared from 1,3-di-cyclohexylmethyl xanthine and chloroacetone using an analogous procedure to that described in Example 5. The title compound was isolated as a crystalline solid, m.p. 153° C.

Sources & evidence

ORD record
ord-774d2636a6cb47f39855105178aaf537
Source dataset
uspto-grants-1994_06
Patent number
US05321029

Reaction notes

Loading…