Chloroacetone → HCID 19020645, compound

HRID 1109490Notes

Reaction equation

[CH:1]1([N:7]2[C:16](=[O:17])[C:15]3[NH:14][CH:13]=[N:12][C:11]=3[N:10]([CH:18]3[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]3)[C:8]2=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.Cl[CH2:25][C:26](=[O:28])[CH3:27]>>[CH:1]1([N:7]2[C:16](=[O:17])[C:15]3[N:14]([CH2:25][C:26](=[O:28])[CH3:27])[CH:13]=[N:12][C:11]=3[N:10]([CH:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[C:8]2=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 6571Chloroacetone

HCID 18624521HCID 18624521, compound

Product 1

HCID 19020645HCID 19020645, compound

Procedure

1,3-Di-cyclohexyl-7-(2-oxopropyl)-xanthine was prepared from 1,3-di-cyclohexyl xanthine and chloroacetone using an analogous procedure to that described in Example 5. The title compound was isolated as a crystalline solid, m.p. 185° C.

Sources & evidence

ORD record: ord-0b03e9b4673740f1abe70ef2402f950f
Source dataset: uspto-grants-1994_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05321029

Reaction notes

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